All about hematology and hemato-oncology
This quiz has 25 Basic and Practical Questions from Transfusion Medicine which a hematologist or haemato oncologists should know. Questions are derived and referenced mainly from book Hematology Oncology Therapy 2nd Ed. All 25 questions are TRUE/FALSE types and answers, Read More …
β-lactam antibiotics (beta-lactam antibiotics) are antibiotics that contain a beta-lactam ring in their chemical structure. This includes penicillin derivatives, cephalosporins and cephamycins, monobactams (aztreonam), carbapenems and carbacephems. These β-lactam antibiotics are cornerstone of treatment of gram-negative bacterial (GNB) sepsis. However, Read More …
An essential component of allogeneic and autologous hematopoietic stem cell transplantation (HSCT) is the conditioning regimen administered before the hematopoietic cell infusion. This post is about basic concepts of conditioning regimens in allogeneic HSCT. Concept of conditioning has evolved over Read More …
Some important points:- PRBC transfusion in Primary Warm AIHA is done only if: HB < 5 g/dl or there is life threatening anemia at presentation. Clinical judgment is most critical at a hemoglobin level of 5 to 8 g/dL. At Read More …
Some Salient Points:- Asymptomatic WM cases don’t require emergent treatment and can be followed up. IgM MGUS cases associated with Peripheral Neuropathy (without fitting into WM/IgM MM criteria) require treatment provided other causes of neuropathy has been ruled out by Read More …
A 27 year old male presented with pain in the left scapular region x 1 months. On examination 2 x 2 cm left axillary node was noted. No hepatosplenomegaly and no other palpable peripheral nodes were seen. Relevant Blood parameters Read More …
A 20-year-old male with newly diagnosed AML (NPM 1 mutated) was started on 3+7 induction. His baseline CT showed a patchy consolidation in the right middle lobe with ground glass opacities along with few ground glass opacities in the right Read More …
Tropical Pulmonary EosinophiliaLook for TPE in patients presenting with Hypereosinophilia.Peripheral eosinophilia, elevated serum IgE and antifilarial antibody detection is crucial for diagnosis along with characteristic radiology on CT thorax. — HemUpdates (@HemUpdates) November 4, 2021 NCCT Thorax shows innumerable tiny Read More …
The human major histocompatibility complex (MHC) is a 7.6‐megabase (Mb) region on the short arm of chromosome 6 that contains more than 300 genes, approximately 20–30% of which have immune‐related function. For a given HLA locus, the antigens encoded by Read More …
Ocular adnexal Lymphomas comprise approximately 1% to 2% of non-Hodgkin lymphomas (NHLs) and 8% of extranodal lymphomas. The most common subtype, accounting for up to 80% of cases of primary ocular adnexal lymphoma (POAL), is marginal zone lymphoma of mucosa-associated Read More …