Transfusion Medicine Review 1

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This quiz has 25 Basic and Practical Questions from Transfusion Medicine which a hematologist or haemato oncologists should know. Questions are derived and referenced mainly from book Hematology Oncology Therapy 2nd Ed. All 25 questions are TRUE/FALSE types and answers, and explanation can be seen immediately after selecting answer and clicking on See Answer. 

This quiz has 25 Basic and Practical Questions from Transfusion Medicine which a hematologist or haemato oncologists should know. Questions are derived and referenced mainly from book Hematology Oncology Therapy 2nd Ed. All 25 questions are TRUE/FALSE types. 

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Question 1 of 25

1. Platelets and granulocytes are not functional in whole blood units.
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B.
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Question 2 of 25

2. RBCs are administered over a maxium period of 4 hours thruough a 100-micro m filter.
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B.
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Question 2 of 25

Question 3 of 25

3. In most stable asymptomatic patients without cardovascular disease, PRBC transfusion is initiated if hemoglobin is <10 g/dL.
A.
B.
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Question 3 of 25

Question 4 of 25

4. Shelf life of PRBC units is 35 days in CPDA- 1
A.
B.
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Question 4 of 25

Question 5 of 25

5. Washed PRBC units are used in patients with severe IgA deficiency.
A.
B.
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Question 6 of 25

6. Shelf life of Washed PRBC unit is 4 days. 
A.
B.
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Question 6 of 25

Question 7 of 25

7. Leucocyte reduced PRBC units are defined by those containing <10 X 106 WBCs per unit. 
A.
B.
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Question 7 of 25

Question 8 of 25

8. Single-donor aphersis Platelets are collected from single donors by apheresis and it contains >/= 3 X 1011 platelets in 250-300 mL plasma.
A.
B.
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Question 8 of 25

Question 9 of 25

9. Shelf life of SDP (Single donor platelets) is 5 days. 
A.
B.
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Question 9 of 25

Question 10 of 25

10. When replacing coagulation factors, a dose of 50 mL/kg of FFP is recommended, with periodic monitoring of coagulation tests to determine efficacy and appropriate dosing intervals.
A.
B.
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Question 10 of 25

Question 11 of 25

11. Each unit (bag) of cryoprecipitate increases fibrinogen level by 5-10 mg/dL in a normal adult. 
A.
B.
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Question 11 of 25

Question 12 of 25

12. RBCs, platelets, and graulocytes are irradiated with 50 G of gamma radiation to prepare irradiated products.
A.
B.
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Question 12 of 25

Question 13 of 25

13. All cellular components that are Leukoreduced are considered “CMV-safe”.
A.
B.
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Question 13 of 25

Question 14 of 25

14. Leukoreduction of blood products prevents TA-GVHD (Transfusion associated graft versus host disease).
A.
B.
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Question 14 of 25

Question 15 of 25

15. FFP and cryoprecipitate do not transmit CMV infection. 
A.
B.
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Question 15 of 25

Question 16 of 25

16. Intravascular hemolysis, renal dysfunction, and progression to DIC are rare with delayed hemolytic transfusion reactions (DHTR).
A.
B.
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Question 16 of 25

Question 17 of 25

17. Patient with frequent febrile reactions should receive leukoreduced products.
A.
B.
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Question 17 of 25

Question 18 of 25

18. IgA deficiency must be excluded when anaphylactic reactions develop to blood products.
A.
B.
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Question 18 of 25

Question 19 of 25

19. Typical features of TRALI include acute respiratory distress, tachycardia, raised blood pressure and evidence of positive fluid balance.
A.
B.
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Question 19 of 25

Question 20 of 25

20. TRALI results from the transfusion of plasma containing blood components.
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B.
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Question 20 of 25

Question 21 of 25

21. In an emergency when blood groups are not available O Rh(D) negative unit is most suitable for transfusion of FFP.
A.
B.
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Question 21 of 25

Question 22 of 25

22. Child with sickle cell disease on a regular transfusion program is most likely to have positive antibody screen.
A.
B.
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Question 22 of 25

Question 23 of 25

23. Neonatal Alloimmune Thrombocytopenia (NAIT), especially with a low platelet count (< 30 – 50,000 plts/µl), will require a platelet transfusion and fathers aphresis platelet is best source of PLT in such neonates.
A.
B.
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Question 23 of 25

Question 24 of 25

24. Intracellular 2,3 DPG falls and approaches zero by 14 days of storage but then returns to normal levels in 24 hours after transfusion to the recipient.
A.
B.
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Question 24 of 25

Question 25 of 25

25. A patient with TTP undergoing therapeutic apheresis (Plasmaphresis) requires cryoprecipitate priming before plasma is administered.
A.
B.
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Question 25 of 25


 

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